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Small Non-Coding Rnas in Prokaryotes epub
Small Non-Coding Rnas in Prokaryotes epub
Small Non-Coding Rnas in Prokaryotes by Christian G Ramos
---------------------------------------------------------------
Author: Christian G Ramos
Number of Pages: 84 pages
Published Date: 09 Jun 2010
Publisher: LAP Lambert Academic Publishing
Publication Country: Germany
Language: English
Format: PDF
ISBN: 9783838321165
File Name: Small.Non-Coding.Rnas.in.Prokaryotes.pdf
Download Link: Small Non-Coding Rnas in Prokaryotes
---------------------------------------------------------------
More than 140 bacterial small non-coding RNAs (sRNAs) have been discovered in Escherichia coli and other bacteria, most of them pathogenic. The sRNA genes are typically encoded in intergenic regions and range from 50 to 500 nucleotides long. Evidences accumulated over the last years point out that sRNAs act as major regulators of adaptive responses at the post-transcriptional level. The mechanisms by which sRNAs modulate the expression of its targets often involve the interaction with their mRNA targets, mediated by the Hfq protein a RNA chaperone. The RNA chaperone Hfq, has been shown to play multiple roles in the biology of bacteria, acting as a pleiotropic regulator. In recent years, the vast majority of sRNAs have been identified by bioinformatics, as is the case of the 213 putative sRNA genes in B. cenocepacia J2315. Preliminary identification and target prediction of Hfq-dependent sRNAs raise interesting questions. The roles played by sRNAs in gene regulation, their interdependence of Hfq and their potential as suitable targets for the development of new antimicrobials is presented and discussed.
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Small Non-Coding Rnas in Prokaryotes by Christian G Ramos
Author: Christian G Ramos
Number of Pages: 84 pages
Published Date: 09 Jun 2010
Publisher: LAP Lambert Academic Publishing
Publication Country: Germany
Language: English
Format: PDF
ISBN: 9783838321165
File Name: Small.Non-Coding.Rnas.in.Prokaryotes.pdf
Download Link: Small Non-Coding Rnas in Prokaryotes
---------------------------------------------------------------
More than 140 bacterial small non-coding RNAs (sRNAs) have been discovered in Escherichia coli and other bacteria, most of them pathogenic. The sRNA genes are typically encoded in intergenic regions and range from 50 to 500 nucleotides long. Evidences accumulated over the last years point out that sRNAs act as major regulators of adaptive responses at the post-transcriptional level. The mechanisms by which sRNAs modulate the expression of its targets often involve the interaction with their mRNA targets, mediated by the Hfq protein a RNA chaperone. The RNA chaperone Hfq, has been shown to play multiple roles in the biology of bacteria, acting as a pleiotropic regulator. In recent years, the vast majority of sRNAs have been identified by bioinformatics, as is the case of the 213 putative sRNA genes in B. cenocepacia J2315. Preliminary identification and target prediction of Hfq-dependent sRNAs raise interesting questions. The roles played by sRNAs in gene regulation, their interdependence of Hfq and their potential as suitable targets for the development of new antimicrobials is presented and discussed.
Read online Small Non-Coding Rnas in Prokaryotes Buy and read online Small Non-Coding Rnas in Prokaryotes Download and read Small Non-Coding Rnas in Prokaryotes for pc, mac, kindle, readers Download to iPad/iPhone/iOS, B&N nook Small Non-Coding Rnas in Prokaryotes
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